Updated List of Top Active Investors & VCs Funding AI Startups in the US in 2025

Last update to database: October 13, 2025

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Leading Investors & Venture Capital Firms Funding Artificial Intelligence Startups Across the US

The United States continues to lead global investment in artificial intelligence in 2025, with record levels of venture capital fueling innovation across the sector. The top active investors and VCs funding AI startups in the US are supporting breakthroughs in machine learning, generative AI, robotics, computer vision, and data infrastructure.


These investors are backing founders across major technology hubs such as San Francisco, New York, Boston, and Austin. They’re providing capital and expertise to help early- and growth-stage AI companies scale domestically and globally.


Our database highlights investors currently funding and supporting AI startups across the United States. Updated weekly, it provides founders, analysts, and business development teams with real-time insights into who’s actively investing in the American artificial intelligence ecosystem.

Comprehensive Database of Active Investors & VCs Funding AI Startups in the US – Updated Weekly

This data is delayed by 4 weeks. Subscribe for instant access to real-time funding rounds and contact data.

Investor Name
Industry Focus Recent Investments Recent Investment Date Check Size Stage Focus Geography Focus Company Headquarters Firm Type Portfolio Size Portfolio Highlights Co-Investor Network
Coho Deeptech Artificial Intelligence, Biotechnology, Blockchain & Cryptocurrency, Health Care & Wellness, SaaS & Software Subscribe to Unlock Subscribe to Unlock September, 2025 $1M-$10M Angel, Pre-Seed, Seed United States, Cayman Islands, Singapore San Francisco, California, United States Venture Capital 17 Subscribe to Unlock Subscribe to Unlock Wayfarer Foundation, Polychain, Y Combinator, Khosla Ventures, Matrix Partners
SV Angel Enterprise Applications, Consumer, High Tech, Financial Services & FinTech, Media & Content Creation Subscribe to Unlock Subscribe to Unlock September, 2025 $100k-$250k Seed, Series A United States, San Francisco San Francisco, California, United States Venture Capital 756 Subscribe to Unlock Subscribe to Unlock Andreessen Horowitz, Forerunner Ventures, Menlo Ventures, SignalFire, Bain Capital Ventures
Lombardstreet Ventures Business & Professional Services, SaaS & Software, Developer Tools, Artificial Intelligence, Infrastructure Software Subscribe to Unlock Subscribe to Unlock September, 2025 $100k-$250k Pre-Seed, Seed United States, Silicon Valley Menlo Park, California, United States Venture Capital 90 Subscribe to Unlock Subscribe to Unlock Unknown
SemperVirens Health Care & Wellness, Financial Services & FinTech, SaaS & Software, Artificial Intelligence, Business & Professional Services Subscribe to Unlock Subscribe to Unlock September, 2025 $1M-$10M Pre-Seed, Seed, Series A United States, San Mateo, San Francisco San Francisco, California, United States Venture Capital 49 Subscribe to Unlock Subscribe to Unlock Index Ventures, General Catalyst, Kraken Ventures, Google Ventures
UPMC Biotechnology, Health Care & Wellness, Artificial Intelligence, Digital Health, SaaS & Software Subscribe to Unlock Subscribe to Unlock September, 2025 $10M-$20M Series A, Series B, Series C United States Pittsburgh, Pennsylvania, United States Corporate VC 40 Subscribe to Unlock Subscribe to Unlock Unknown
HighSage Ventures SaaS & Software, Financial Services & FinTech, Business & Professional Services, Consumer, Data & Analytics Subscribe to Unlock Subscribe to Unlock September, 2025 $1M-$10M Pre-Seed, Seed, Series A, Series B, Series C, Series D United States, Europe Boston, Massachusetts, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Juniper Square, Addepar, Klaviyo, Lattice, Cherre
Informed Ventures Artificial Intelligence, Digital Health, SaaS & Software, Health Care & Wellness, Information Technology Subscribe to Unlock Subscribe to Unlock September, 2025 $500k-$1M Pre-Seed, Seed, Series A United States Menlo Park, California, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock GSR Ventures, Data Collective DCVC, Lux Capital, First Round Capital, Sequoia Capital
Coinbase Blockchain & Cryptocurrency, Financial Services & FinTech, Apps & Platforms, Data & Analytics, SaaS & Software Subscribe to Unlock Subscribe to Unlock October, 2025 $1M-$10M Seed, Series A, Series B, Series C, Series D United States San Francisco, California, United States Corporate VC 461 Subscribe to Unlock Subscribe to Unlock Pantera Capital, Andreessen Horowitz, Polychain Capital, Dragonfly, Alameda Research
JME Ventures SaaS & Software, Information Technology, Financial Services & FinTech, EdTech and Training, Apps & Platforms Subscribe to Unlock Subscribe to Unlock September, 2025 $100k-$1M Seed, Series A Europe, United States, Spain Madrid, Community of Madrid, Spain Venture Capital 70 Subscribe to Unlock Subscribe to Unlock Top global investors and operators (not specifically named)
Lumio Capital Health Care & Wellness, EdTech and Training, SaaS & Software, Artificial Intelligence, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock September, 2025 $1M-$10M Pre-Seed, Seed, Series A North America, Europe United Arab Emirates Venture Capital 20 Subscribe to Unlock Subscribe to Unlock Unknown
Circle Blockchain & Cryptocurrency, Financial Services & FinTech, Apps & Platforms, SaaS & Software Subscribe to Unlock Subscribe to Unlock October, 2025 $1M-$10M Seed, Series A, Series B North America, Europe Boston, Massachusetts, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Dragonfly Capital, Placeholder Capital, Multicoin Capital, Polychain Capital
OXZ Capital Technology, Real Estate, Agriculture, SaaS & Software, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock September, 2025 $1M-$10M Seed, Series A, Series B, Series C, Series D Asia, Singapore, United States Singapore, Central Region, Singapore Venture Capital 30 Subscribe to Unlock Subscribe to Unlock Alpha JWC Ventures, Access Ventures, Dymon Asia Venture, Wavemaker Partners, Monk’s Hill Ventures
GFT Ventures Artificial Intelligence, Blockchain & Cryptocurrency, SaaS & Software, Data & Analytics, Information Technology Subscribe to Unlock Subscribe to Unlock September, 2025 $1M-$10M Seed, Series A United States, Israel, South Korea Palo Alto, California, United States Venture Capital 41 Subscribe to Unlock Subscribe to Unlock NextEquity Partners, Menlo Ventures, Liberty City Ventures
Orascom Manufacturing, Construction, Infrastructure, Industrial, Facility Management Subscribe to Unlock Subscribe to Unlock September, 2025 $20M+ Series B, Series C, Series D Middle East, Africa, United States Cairo, Egypt Corporate VC 15 Subscribe to Unlock Subscribe to Unlock Unknown
Khosla Ventures Artificial Intelligence, Health Care & Wellness, GreenTech & Sustainability, SaaS & Software, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock October, 2025 $1M–$10M Pre-seed, Seed, Series A, Series B, Growth United States, Global Menlo Park, California, United States Venture Capital 100 Subscribe to Unlock Subscribe to Unlock Unknown
American Family Ventures Insurance, Financial Services & FinTech, Artificial Intelligence, SaaS & Software, Data & Analytics Subscribe to Unlock Subscribe to Unlock October, 2025 $500k–$1M Pre-seed, Seed, Series A, Growth United States United States Corporate VC 159 Subscribe to Unlock Subscribe to Unlock MassMutual Ventures, Plug and Play Tech Center, General Catalyst, IA Capital Group, TriplePoint Capital
Y Combinator Apps & Platforms, SaaS & Software, Artificial Intelligence, Biotechnology, EdTech and Training Subscribe to Unlock Subscribe to Unlock October, 2025 $500k-$1M Pre-Seed, Seed, Series A, Series B United States, North America United States Accelerator 5000 Subscribe to Unlock Subscribe to Unlock Top startup investors (network introduced by YC)
E& Software & Platforms, Cyber Security & Privacy, GreenTech & Sustainability, Data & Analytics, Science & Engineering Subscribe to Unlock Subscribe to Unlock September, 2025 $1M-$10M Seed, Series A, Series B Europe, Germany Abu Dhabi, United Arab Emirates Venture Capital 88 Subscribe to Unlock Subscribe to Unlock TGFS, European Union, EIC Fund
VentureFriends SaaS & Software, Marketplaces, Financial Services & FinTech, E-Commerce & Retail, Business & Professional Services Subscribe to Unlock Subscribe to Unlock September, 2025 $500k-$1M Pre-Seed, Seed Europe, Middle East Athens, Greece Venture Capital 100 Subscribe to Unlock Subscribe to Unlock Accel, Index Ventures, Balderton Capital
Earlybird Financial Services & FinTech, SaaS & Software, Energy, Food & Drink, Science & Engineering Subscribe to Unlock Subscribe to Unlock September, 2025 $1M-$10M Pre-Seed, Seed, Series A Europe, Germany, United Kingdom, France Berlin, Berlin, Germany Venture Capital 100 Subscribe to Unlock Subscribe to Unlock Unknown
Accel SaaS & Software, Information Technology, Financial Services & FinTech, Health Care & Wellness, Artificial Intelligence Subscribe to Unlock Subscribe to Unlock October, 2025 $1M-$10M Seed, Series A, Series B, Series C, Series D United States, United Kingdom, India, China Palo Alto, California, United States Venture Capital 1133 Subscribe to Unlock Subscribe to Unlock Y Combinator, Sequoia Capital, Tiger Global Management, Insight Partners, Lightspeed Venture Partners
General Catalyst Artificial Intelligence, Health Care & Wellness, Financial Services & FinTech, SaaS & Software, Enterprise Subscribe to Unlock Subscribe to Unlock October, 2025 $1M–$10M Seed, Series A, Series B, Growth North America, Europe, Asia Cambridge, Massachusetts, United States Venture Capital 800 Subscribe to Unlock Subscribe to Unlock GC Famiglia (community of CEOs, founders, partners, policymakers)
New Enterprise Associates Health Care & Wellness, Information Technology, SaaS & Software, Biotechnology, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock October, 2025 $1M-$10M Seed, Series A, Series B, Series C, Series D United States, Europe, Asia Menlo Park, California, United States Venture Capital 450 Subscribe to Unlock Subscribe to Unlock ARCH Venture Partners, Foresite Labs, Lux Capital, Lightspeed Venture Partners, Sequoia Capital
Augur Vc Artificial Intelligence, Energy, SaaS & Software Subscribe to Unlock Subscribe to Unlock September, 2025 $100k-$250k Pre-Seed, Seed North America Calgary, Alberta, Canada Venture Capital 11 Subscribe to Unlock Subscribe to Unlock Unknown
GreatPoint Ventures Health Care & Wellness, Biotechnology, Enterprise Technology (Apps & Platforms, SaaS & Software), Artificial Intelligence, Food & Drink Subscribe to Unlock Subscribe to Unlock September, 2025 $250k-$20M Seed, Series A, Series B North America, United States, San Francisco San Francisco, California, United States Venture Capital 86 Subscribe to Unlock Subscribe to Unlock Andreessen Horowitz, Sequoia Capital, New Relic
BroadLight Capital Technology, Consumer, Media & Entertainment Subscribe to Unlock Subscribe to Unlock September, 2025 $1M-$10M Series A, Series B, Series C United States New York, New York, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Unknown
Anthropic Artificial Intelligence, Information Technology, SaaS & Software, Data & Analytics, Business & Professional Services Subscribe to Unlock Subscribe to Unlock October, 2025 $1M-$10M Series C, Series D United States San Francisco, California, United States Other 10 Subscribe to Unlock Subscribe to Unlock ICONIQ, Lightspeed Venture Partners, Fidelity Management & Research Company, Altimeter, Baillie Gifford
Menlo Ventures Artificial Intelligence, Biotechnology, Cyber Security & Privacy, Financial Services & FinTech, SaaS & Software Subscribe to Unlock Subscribe to Unlock October, 2025 $1M–$10M Seed, Series A, Series B United States, Canada Menlo Park, California, United States Venture Capital 100 Subscribe to Unlock Subscribe to Unlock Anthropic
Insight Partners SaaS & Software, Cyber Security & Privacy, Financial Services & FinTech, Health Care & Wellness, Information Technology Subscribe to Unlock Subscribe to Unlock October, 2025 $10M–$20M Series A, Series B, Growth, Late-stage United States, Europe, Israel New York, New York, United States Venture Capital 800 Subscribe to Unlock Subscribe to Unlock Sequoia Capital, Accel, Tiger Global Management, TCV
Foundation Capital Artificial Intelligence, Enterprise, Financial Services & FinTech, Blockchain & Cryptocurrency, SaaS & Software Subscribe to Unlock Subscribe to Unlock October, 2025 $500k-$1M Seed, Series A, Series B United States Palo Alto, California, United States Venture Capital 385 Subscribe to Unlock Subscribe to Unlock Andreessen Horowitz, Sequoia Capital, Accel, Greylock Partners
Base10 Partners Financial Services & FinTech, SaaS & Software, Enterprise Applications, Artificial Intelligence, Business & Professional Services Subscribe to Unlock Subscribe to Unlock October, 2025 $1M–$10M Seed, Series A United States, San Francisco San Francisco, California, United States Venture Capital 128 Subscribe to Unlock Subscribe to Unlock Tiger Global Management, Y Combinator, Andreessen Horowitz, SVB, Headline
Crosspoint Capital Cyber Security & Privacy, Information Technology, SaaS & Software, Artificial Intelligence, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock September, 2025 $10M-$20M Series A, Series B, Series C, Series D United States Menlo Park, California, United States Private Equity 11 Subscribe to Unlock Subscribe to Unlock Silver Lake Partners, Thoma Bravo, KKR, Vista Equity Partners, Insight Partners
Shield Capital Artificial Intelligence, Cyber Security & Privacy, Aerospace & Autonomy (classified under Miscellaneous), SaaS & Software, Data & Analytics Subscribe to Unlock Subscribe to Unlock September, 2025 $500k-$1M Pre-Seed, Seed, Series A United States, San Francisco San Francisco, California, United States Venture Capital 15 Subscribe to Unlock Subscribe to Unlock Unknown
Scale Venture Partners SaaS & Software, Artificial Intelligence, Cyber Security & Privacy, Financial Services & FinTech, Data & Analytics Subscribe to Unlock Subscribe to Unlock September, 2025 $1M-$10M Series A, Series B, Series C United States, San Francisco Bay Area, New York Foster City, California, United States Venture Capital 380 Subscribe to Unlock Subscribe to Unlock NFX, DFJ, Comcast Ventures, Sequoia Capital, Andreessen Horowitz
Idea Fund Information Technology, Health Care & Wellness, Data & Analytics, Manufacturing, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock September, 2025 $500k-$1M Pre-Seed, Seed, Series A United States, Wisconsin, Iowa, Minnesota, Upper Midwest La Crosse, Wisconsin, United States Venture Capital 15 Subscribe to Unlock Subscribe to Unlock Unknown
HOF Capital Artificial Intelligence, Biotechnology, Financial Services & FinTech, Science & Engineering, SaaS & Software Subscribe to Unlock Subscribe to Unlock September, 2025 $100k-$250k Angel, Pre-Seed, Seed, Series A, Series B, Series C, Series D North America, South America, Europe, Africa, Asia New York, New York, United States Venture Capital 100 Subscribe to Unlock Subscribe to Unlock Unknown
Bain Capital Ventures Financial Services & FinTech, E-Commerce & Retail, Apps & Platforms, Artificial Intelligence, Health Care & Wellness Subscribe to Unlock Subscribe to Unlock October, 2025 $1M-$10M Seed, Series A, Series B, Series C United States San Francisco, California, United States Venture Capital 400 Subscribe to Unlock Subscribe to Unlock Unknown
Mucker Capital SaaS & Software, Information Technology, Apps & Platforms Subscribe to Unlock Subscribe to Unlock September, 2025 $500k-$1M Seed, Series A United States, Canada Venice, California, United States Venture Capital 90 Subscribe to Unlock Subscribe to Unlock Unknown
Andreessen Horowitz Artificial Intelligence, Biotechnology, Blockchain & Cryptocurrency, Financial Services & FinTech, Gaming Subscribe to Unlock Subscribe to Unlock October, 2025 $500k–$1M Pre-seed, Seed, Series A, Series B, Growth, Late-stage North America, United States Menlo Park, California, United States Venture Capital 1000 Subscribe to Unlock Subscribe to Unlock Thrive Capital, General Catalyst, Alumni Ventures, Sequoia Capital, Accel
Ten Eleven Ventures Cyber Security & Privacy, Information Technology, Communication & IT, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock September, 2025 $1M-$10M Seed, Series A, Series B United States Burlingame, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Unknown
Greycroft SaaS & Software, Artificial Intelligence, Sustainability, Consumer Brands, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock October, 2025 $1M-$10M Seed, Series A, Series B, Series C United States New York, New York, United States Venture Capital 400 Subscribe to Unlock Subscribe to Unlock Sequoia Capital, Andreessen Horowitz, Accel, Lightspeed Venture Partners, General Catalyst
Abstract Biotechnology, Blockchain & Cryptocurrency, SaaS & Software, Financial Services & FinTech, Artificial Intelligence Subscribe to Unlock Subscribe to Unlock October, 2025 $1M-$10M Seed, Series A United States San Francisco, California, United States Venture Capital 150 Subscribe to Unlock Subscribe to Unlock Unknown
Bullpen Capital Gaming, E-Commerce & Retail, SaaS & Software, Health Care & Wellness, Apps & Platforms Subscribe to Unlock Subscribe to Unlock September, 2025 $500k-$1M Seed, Series A United States San Francisco, California, United States Venture Capital 100 Subscribe to Unlock Subscribe to Unlock Unknown
Shadow Ventures ConstructionTech, PropTech, Design & Innovation, GreenTech & Sustainability, SaaS & Software Subscribe to Unlock Subscribe to Unlock September, 2025 $250k-$500k Pre-Seed, Seed United States Atlanta, Georgia, United States Venture Capital 48 Subscribe to Unlock Subscribe to Unlock GroundBreak Ventures, RET Ventures, Second Century Ventures, UnitLeader
TenOneTen Ventures Health Care & Wellness, Logistics & Transportation, Property & Real Estate, Artificial Intelligence, SaaS & Software Subscribe to Unlock Subscribe to Unlock September, 2025 $500k–$1M Pre-Seed, Seed, Series A United States, Los Angeles Los Angeles, California, United States Venture Capital 50 Subscribe to Unlock Subscribe to Unlock Andreessen Horowitz (a16z), M13, IBank, Matter Venture Partners, Crosscut Ventures
Touring Capital Artificial Intelligence, SaaS & Software, Business & Professional Services Subscribe to Unlock Subscribe to Unlock September, 2025 $1M-$10M Series B, Series C United States San Francisco, California, United States Venture Capital 10 Subscribe to Unlock Subscribe to Unlock Unknown
Link Ventures Artificial Intelligence, Financial Services & FinTech, Health Care & Wellness, E-Commerce & Retail, Cyber Security & Privacy Subscribe to Unlock Subscribe to Unlock September, 2025 $500k-$1M Pre-Seed, Seed, Series A United States, North America, Global Cambridge, Massachusetts, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Unknown
A2D Ventures Artificial Intelligence, SaaS & Software, Financial Services & FinTech, Health Care & Wellness, E-Commerce & Retail Subscribe to Unlock Subscribe to Unlock September, 2025 $250k-$500k Pre-Seed, Seed, Series A Asia, Singapore, Thailand, Vietnam, Malaysia, Indonesia, Philippines Bangkok, Thailand Angel Investor 17 Subscribe to Unlock Subscribe to Unlock BEENEXT, East Ventures, Golden Gate Ventures, Wavemaker Partners
Hanaco Ventures Food & Drink, Health Care & Wellness, Financial Services & FinTech, SaaS & Software, Artificial Intelligence Subscribe to Unlock Subscribe to Unlock September, 2025 $1M-$10M Seed, Series A, Series C United States, Israel, Europe Herzliya, Israel Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Sequoia Capital, Battery Ventures, Insight Partners, Bessemer Venture Partners
South Park Commons Apps & Platforms, Blockchain & Cryptocurrency, EdTech and Training, Financial Services & FinTech, SaaS & Software Subscribe to Unlock Subscribe to Unlock October, 2025 $500k–$1M Pre-Seed, Seed North America, United States, San Francisco San Francisco, California, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Unknown

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