Updated List of Top Active Investors & VCs Based in the US in 2025
Last update to database: October 13, 2025
Leading Investors & Venture Capital Firms Headquartered in the United States
In 2025, the US continues to serve as the central hub for global venture capital and private investment activity. The top active investors and VCs based in the United States are leading the charge in funding innovation across every major sector—from AI and fintech to health tech, SaaS, and clean energy.
These US-headquartered firms operate from major centers like San Francisco, New York, and Boston, but their investment reach extends worldwide. They’re not just providing capital—they’re backing visionary founders and shaping the next generation of high-growth companies.
Our database highlights investors and venture capital firms headquartered in the US who are currently active in startup funding. Updated weekly, it’s the most comprehensive source for discovering the firms driving venture activity across the United States.
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Updated List of Top Active Investors & VCs Based in the US in 2025
Last update to database: October 13, 2025
Subscribe to Unlock Active Startup Investors
Request AccessConnect with active investors funding startups in your region or industry. Subscribe to unlock full firm and contact data.
Leading Investors & Venture Capital Firms Headquartered in the United States
In 2025, the US continues to serve as the central hub for global venture capital and private investment activity. The top active investors and VCs based in the United States are leading the charge in funding innovation across every major sector—from AI and fintech to health tech, SaaS, and clean energy.
These US-headquartered firms operate from major centers like San Francisco, New York, and Boston, but their investment reach extends worldwide. They’re not just providing capital—they’re backing visionary founders and shaping the next generation of high-growth companies.
Our database highlights investors and venture capital firms headquartered in the US who are currently active in startup funding. Updated weekly, it’s the most comprehensive source for discovering the firms driving venture activity across the United States.
Comprehensive Database of Active Investors & VCs Based in the US – Updated Weekly
This data is delayed by 4 weeks. Subscribe for instant access to real-time funding rounds and contact data.
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Investor Name
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Industry Focus | Recent Investments | Recent Investment Date | Check Size | Stage Focus | Geography Focus | Company Headquarters | Firm Type | Portfolio Size | Portfolio Highlights | Co-Investor Network |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Andreessen Horowitz | Artificial Intelligence, Biotechnology, Blockchain & Cryptocurrency, Financial Services & FinTech, Gaming | Subscribe to Unlock Subscribe to Unlock | October, 2025 | $500k–$1M | Pre-seed, Seed, Series A, Series B, Growth, Late-stage | North America, United States | Menlo Park, California, United States | Venture Capital | 1000 | Subscribe to Unlock Subscribe to Unlock | Thrive Capital, General Catalyst, Alumni Ventures, Sequoia Capital, Accel |
| Abstract | Biotechnology, Blockchain & Cryptocurrency, SaaS & Software, Financial Services & FinTech, Artificial Intelligence | Subscribe to Unlock Subscribe to Unlock | October, 2025 | $1M-$10M | Seed, Series A | United States | San Francisco, California, United States | Venture Capital | 150 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Accel | SaaS & Software, Information Technology, Financial Services & FinTech, Health Care & Wellness, Artificial Intelligence | Subscribe to Unlock Subscribe to Unlock | October, 2025 | $1M-$10M | Seed, Series A, Series B, Series C, Series D | United States, United Kingdom, India, China | Palo Alto, California, United States | Venture Capital | 1133 | Subscribe to Unlock Subscribe to Unlock | Y Combinator, Sequoia Capital, Tiger Global Management, Insight Partners, Lightspeed Venture Partners |
| Plug And Play Tech Center | Enterprise & AI, FinTech, Energy, AgriTech & Farming, Health Care & Wellness | Subscribe to Unlock Subscribe to Unlock | October, 2025 | $25k-$500k | Seed, Series A | United States, United Kingdom, Canada, Asia, Europe | Sunnyvale, California, United States | Accelerator | 1661 | Subscribe to Unlock Subscribe to Unlock | 500 Global, Sequoia Capital, Andreessen Horowitz |
| Co Ventures | SaaS & Software, Health Care & Wellness, Business & Professional Services, Manufacturing | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $1M-$10M | Seed | Australia | San Francisco, California, United States | Venture Capital | 2 | Subscribe to Unlock Subscribe to Unlock | Blackbird Ventures, Archangel |
| Draper Associates | Artificial Intelligence, Robotics & Automation, Biotechnology, Blockchain & Cryptocurrency, Aerospace & Space | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $250k-$500k | Angel, Pre-Seed, Seed | Global, United States | San Mateo, California, United States | Venture Capital | 400 | Subscribe to Unlock Subscribe to Unlock | Andreessen Horowitz, Sequoia Capital, Founders Fund, Lightspeed Venture Partners, Accel |
| Coho Deeptech | Artificial Intelligence, Biotechnology, Blockchain & Cryptocurrency, Health Care & Wellness, SaaS & Software | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $1M-$10M | Angel, Pre-Seed, Seed | United States, Cayman Islands, Singapore | San Francisco, California, United States | Venture Capital | 17 | Subscribe to Unlock Subscribe to Unlock | Wayfarer Foundation, Polychain, Y Combinator, Khosla Ventures, Matrix Partners |
| Sutter Hill Ventures | Data & Analytics, SaaS & Software, Artificial Intelligence, Business & Professional Services, Information Technology | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $1M-$10M | Pre-Seed, Seed, Series A, Series B, Series C, Series D | United States, United Kingdom | Palo Alto, California, United States | Venture Capital | 312 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Symphonic Capital | Health Care & Wellness, Financial Services & FinTech | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $500k-$1M | Pre-Seed, Seed | United States | San Diego, California, United States | Venture Capital | 40 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Ten Eleven Ventures | Cyber Security & Privacy, Information Technology, Communication & IT, Financial Services & FinTech | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $1M-$10M | Seed, Series A, Series B | United States | Burlingame, United States | Venture Capital | 40 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Bonsai Partners | SaaS & Software, Financial Services & FinTech, Artificial Intelligence, Business & Professional Services | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $250k-$500k | Seed, Series A | United States | Carlsbad, California, United States | Venture Capital | 40 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Lombardstreet Ventures | Business & Professional Services, SaaS & Software, Developer Tools, Artificial Intelligence, Infrastructure Software | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $100k-$250k | Pre-Seed, Seed | United States, Silicon Valley | Menlo Park, California, United States | Venture Capital | 90 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Mucker Capital | SaaS & Software, Information Technology, Apps & Platforms | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $500k-$1M | Seed, Series A | United States, Canada | Venice, California, United States | Venture Capital | 90 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Automate Health | SaaS & Software, Health Care & Wellness, Business & Professional Services, Artificial Intelligence, Data & Analytics | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $1M-$10M | Seed, Series A | United Kingdom, Europe | Pittsburgh, Pennsylvania, United States | Venture Capital | 20 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| UPMC | Biotechnology, Health Care & Wellness, Artificial Intelligence, Digital Health, SaaS & Software | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $10M-$20M | Series A, Series B, Series C | United States | Pittsburgh, Pennsylvania, United States | Corporate VC | 40 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Moneta Ventures | SaaS & Software, Business & Professional Services, Information Technology, Financial Services & FinTech, Artificial Intelligence | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $1M-$10M | Seed, Series A | United States, California, Texas | Folsom, California, United States | Venture Capital | 25 | Subscribe to Unlock Subscribe to Unlock | Sacramento Angels |
| HOF Capital | Artificial Intelligence, Biotechnology, Financial Services & FinTech, Science & Engineering, SaaS & Software | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $100k-$250k | Angel, Pre-Seed, Seed, Series A, Series B, Series C, Series D | North America, South America, Europe, Africa, Asia | New York, New York, United States | Venture Capital | 100 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Thesis Capital Partners | Health Care & Wellness, SaaS & Software, Business & Professional Services | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $10M-$20M | Other | United States | Houston, Texas, United States | Private Equity | 20 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| The Raine Group | Media & Content Creation, Gaming, Financial Services & FinTech, SaaS & Software, Artificial Intelligence | Subscribe to Unlock Subscribe to Unlock | October, 2025 | $10M-$20M | Series A, Series B, Series C | North America, Europe, Asia | New York, New York, United States | Private Equity | 40 | Subscribe to Unlock Subscribe to Unlock | SoftBank Group, Mubadala Investment Company, William Morris Endeavor, Forstmann, Masayoshi Son |
| BroadLight Capital | Technology, Consumer, Media & Entertainment | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $1M-$10M | Series A, Series B, Series C | United States | New York, New York, United States | Venture Capital | 40 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Norwest | Biotechnology, Financial Services & FinTech, SaaS & Software, Consumer Products, Information Technology | Subscribe to Unlock Subscribe to Unlock | October, 2025 | $1M-$10M | Pre-Seed, Seed, Series A, Series B, Series C, Series D | North America, India, Israel | Menlo Park, California, United States | Venture Capital | 700 | Subscribe to Unlock Subscribe to Unlock | Accel, Citius, Elevation Capital, General Catalyst |
| SV Angel | Enterprise Applications, Consumer, High Tech, Financial Services & FinTech, Media & Content Creation | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $100k-$250k | Seed, Series A | United States, San Francisco | San Francisco, California, United States | Venture Capital | 756 | Subscribe to Unlock Subscribe to Unlock | Andreessen Horowitz, Forerunner Ventures, Menlo Ventures, SignalFire, Bain Capital Ventures |
| Informed Ventures | Artificial Intelligence, Digital Health, SaaS & Software, Health Care & Wellness, Information Technology | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $500k-$1M | Pre-Seed, Seed, Series A | United States | Menlo Park, California, United States | Venture Capital | 40 | Subscribe to Unlock Subscribe to Unlock | GSR Ventures, Data Collective DCVC, Lux Capital, First Round Capital, Sequoia Capital |
| YL Ventures | Cyber Security & Privacy, Communications and Information Technology, Business & Professional Services | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $1M-$10M | Seed, Series A, Series B | United States, Israel | Mill Valley, California, United States | Venture Capital | 35 | Subscribe to Unlock Subscribe to Unlock | StoneMill Ventures, JVP, OurCrowd, Ten Eleven Ventures, Stripes |
| WEX | Electric Vehicle Innovation, Fleet Mobility, Payment Solutions, Energy, Financial Services & FinTech | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $10M-$20M | Pre-Seed, Seed, Series A | North America, Europe, Asia, Latin America | Portland, Maine, United States | Corporate VC | 40 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| HighSage Ventures | SaaS & Software, Financial Services & FinTech, Business & Professional Services, Consumer, Data & Analytics | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $1M-$10M | Pre-Seed, Seed, Series A, Series B, Series C, Series D | United States, Europe | Boston, Massachusetts, United States | Venture Capital | 40 | Subscribe to Unlock Subscribe to Unlock | Juniper Square, Addepar, Klaviyo, Lattice, Cherre |
| Galaxy Ventures | Blockchain & Cryptocurrency, Financial Services & FinTech, Information Technology, Software & SaaS, Artificial Intelligence | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $10M-$20M | Seed, Series A | United States, Belgium, Cayman Islands, France, Russia | New York, New York, United States | Venture Capital | 6 | Subscribe to Unlock Subscribe to Unlock | Wintermute, Delphi Ventures, Faction VC, Founders Fund |
| Foundation Capital | Artificial Intelligence, Enterprise, Financial Services & FinTech, Blockchain & Cryptocurrency, SaaS & Software | Subscribe to Unlock Subscribe to Unlock | October, 2025 | $500k-$1M | Seed, Series A, Series B | United States | Palo Alto, California, United States | Venture Capital | 385 | Subscribe to Unlock Subscribe to Unlock | Andreessen Horowitz, Sequoia Capital, Accel, Greylock Partners |
| Rogue Women's Fund | SaaS & Software, Health Care & Wellness, Business & Professional Services | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $500k-$1M | Pre-Seed, Seed | United States | Portland, Oregon, United States | Venture Capital | 35 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| SustainVC | GreenTech & Sustainability, Health Care & Wellness, EdTech and Training, Financial Services & FinTech, Business & Professional Services | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $500k-$1M | Seed, Series A, Series B | United States, Boston, Durham, Philadelphia | Philadelphia, Pennsylvania, United States | Venture Capital | 45 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Wave Function | Aerospace, Defense, Energy, Infrastructure, Robotics | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $100k-$250k | Pre-Seed, Seed | United States | New Bedford, Massachusetts, United States | Venture Capital | 4 | Subscribe to Unlock Subscribe to Unlock | Black Mountain Ventures, First Round Capital, GOOSE Capital, SGH, Tola Capital |
| Anthropic | Artificial Intelligence, Information Technology, SaaS & Software, Data & Analytics, Business & Professional Services | Subscribe to Unlock Subscribe to Unlock | October, 2025 | $1M-$10M | Series C, Series D | United States | San Francisco, California, United States | Other | 10 | Subscribe to Unlock Subscribe to Unlock | ICONIQ, Lightspeed Venture Partners, Fidelity Management & Research Company, Altimeter, Baillie Gifford |
| Forerunner | E-Commerce & Retail, Financial Services & FinTech, Health Care & Wellness, SaaS & Software, Artificial Intelligence | Subscribe to Unlock Subscribe to Unlock | October, 2025 | $1M-$10M | Seed, Series A | United States, North America | San Francisco, California, United States | Venture Capital | 100 | Subscribe to Unlock Subscribe to Unlock | Basic Capital, Sequoia, Accel, Thrive Capital, Benchmark |
| HarbourView | Media & Content Creation, Music & Entertainment, Sports & Fitness Tech, Artificial Intelligence, SaaS & Software | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $1M-$10M | Seed, Series A, Series B | United States | Newark, New Jersey, United States | Venture Capital | 40 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Act III Holdings | Food & Drink, Entertainment, Restaurants, Consumer Services, Hospitality | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $1M-$10M | Seed, Series A, Series B | United States, Europe | Miami, Florida, United States | Venture Capital | 20 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Pear VC | Artificial Intelligence, SaaS & Software, Health Care & Wellness, Financial Services & FinTech, Biotechnology | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $500k–$1M | Pre-seed, Seed | United States | Menlo Park, California, United States | Venture Capital | 400 | Subscribe to Unlock Subscribe to Unlock | Y Combinator, Techstars, National Science Foundation, 500 Global, New Enterprise Associates |
| SJF Ventures | Health Care & Wellness, GreenTech & Sustainability, SaaS & Software, Information Technology, Business & Professional Services | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $1M-$10M | Series A, Series B, Series C | United States | Durham, North Carolina, United States | Venture Capital | 50 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Kindred Ventures | Artificial Intelligence, GreenTech & Sustainability, Financial Services & FinTech, Health Care & Wellness, Logistics & Transportation | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $100k-$250k | Pre-Seed, Seed | United States, France, Brazil, United Kingdom | San Francisco, California, United States | Venture Capital | 100 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Council Capital | Health Care & Wellness | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $10M-$20M | United States | Washington, District of Columbia, United States | Private Equity | 40 | Subscribe to Unlock Subscribe to Unlock | Unknown | |
| Verissimo Ventures | SaaS & Software, Financial Services & FinTech, Health Care & Wellness, Logistics & Transportation, Information Technology | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $500k-$1M | Pre-Seed, Seed | United States, Israel, Europe | Bedford, New Hampshire, United States | Venture Capital | 100 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| NextGen VP | SaaS & Software, Health Care & Wellness, Financial Services & FinTech, Data & Analytics, Robotics | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $500k-$1M | Pre-Seed, Seed, Series A | United States, San Francisco | San Francisco, California, United States | Venture Capital | 100 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Integrity Growth Partners | SaaS & Software, Information Technology, Business & Professional Services, Software, Tech-Enabled Services | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $10M-$20M | Series A, Series B, Series C | United States | Los Angeles, California, United States | Private Equity | 30 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Base10 Partners | Financial Services & FinTech, SaaS & Software, Enterprise Applications, Artificial Intelligence, Business & Professional Services | Subscribe to Unlock Subscribe to Unlock | October, 2025 | $1M–$10M | Seed, Series A | United States, San Francisco | San Francisco, California, United States | Venture Capital | 128 | Subscribe to Unlock Subscribe to Unlock | Tiger Global Management, Y Combinator, Andreessen Horowitz, SVB, Headline |
| Razor's Edge Ventures | Cyber Security & Privacy, Artificial Intelligence, Data & Analytics, Hardware, SaaS & Software | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $1M-$10M | Pre-Seed, Seed, Series A, Series B, Series C, Series D | United States | Reston, Virginia, United States | Venture Capital | 18 | Subscribe to Unlock Subscribe to Unlock | Lockheed Martin Ventures, 3G, Gula Tech Adventures, Insight Partners, Shield Capital |
| MIG Capital | SaaS & Software | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $20M+ | United States | Newport Beach, California, United States | Other | 5 | Subscribe to Unlock Subscribe to Unlock | Unknown | |
| Bain Capital Ventures | Financial Services & FinTech, E-Commerce & Retail, Apps & Platforms, Artificial Intelligence, Health Care & Wellness | Subscribe to Unlock Subscribe to Unlock | October, 2025 | $1M-$10M | Seed, Series A, Series B, Series C | United States | San Francisco, California, United States | Venture Capital | 400 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| NewVale Capital | Enterprise Applications, Health Care & Wellness, Artificial Intelligence, Biotechnology, SaaS & Software | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $10M-$20M | Series B, Series C | United States, Israel | Boulder, Colorado, United States | Venture Capital | 4 | Subscribe to Unlock Subscribe to Unlock | Telegraph Hill Partners, CYwP Funds, Industry Ventures, Crosslink Capital, Atlantic Bridge |
| Overlap Holdings | Energy, Life Sciences & Biotechnology, Materials Science, Space, Robotics, Semiconductors | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $250k-$500k | Seed, Series A, Series B | United States | New York, New York, United States | Venture Capital | 7 | Subscribe to Unlock Subscribe to Unlock | Civilization Ventures, Conscience VC, Illumina Ventures, LifeSpan Vision Ventures, Sutter Hill Ventures |
| Quadri Ventures | SaaS & Software, Artificial Intelligence, Cyber Security & Privacy, Property & Real Estate, Logistics & Transportation | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $1M-$10M | Seed, Series A, Series B | United States, Europe | New York, New York, United States | Venture Capital | 10 | Subscribe to Unlock Subscribe to Unlock | AWS, Nvidia, Anthropic |
| Upfront Ventures | Health Care & Wellness, Artificial Intelligence, Biotechnology, Consumer Products, SaaS & Software | Subscribe to Unlock Subscribe to Unlock | September, 2025 | $500k–$1M | Pre-Seed, Seed, Series A | United States, Europe, India, Israel | Santa Monica, California, United States | Venture Capital | 100 | Subscribe to Unlock Subscribe to Unlock | Unknown |
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